To assess the roles of serial engagement and kinetic proofreading in T cell receptor (TCR) internalization, we have developed a mathematical model of this process. Our determination of TCR ...
Monoclonal antibodies are commonly utilized as anti-inflammatory, anti-cancer and anti-viral therapeutic agents. The location, extent and rate of internalization into cells are considered to be ...
Antibody-Drug Conjugates (ADCs) are a core technology in tumor-targeted therapy, featuring a ‘tripartite integrated design’ of ‘precision carrier-stable linker-potent payload’. The carrier component ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results