Nature

Extracellular vesicles derived from lung M2 macrophages enhance group 2 innate lymphoid cells function in allergic airway inflammation

Group 2 innate lymphoid cells (ILC2s) promote the recruitment of eosinophils by secreting large amounts of type 2 cytokines (IL-5 and IL-13), thus triggering the main feature of asthma, pathological ...
Nature

Integrative multi-omics and machine learning reveal critical functions of proliferating cells in prognosis and personalized treatment of lung adenocarcinoma

Lung adenocarcinoma (LUAD) is a major cause of cancer-related mortality globally. Proliferating cells, crucial components of the tumor immune microenvironment (TIME), play a significant role in cancer ...
Medical Xpress

First breathing 'lung-on-chip' developed using genetically identical cells

Researchers at the Francis Crick Institute and AlveoliX have developed the first human lung-on-chip model using stem cells taken from only one person. These chips simulate breathing motions and lung ...